Fresenius Kabi’s injectable glutamine, 50ml x 10 amp

Fresenius Kabi’s injectable glutamine

A supplement matching a 50ml format packaged in boxes of 10 is known as Dipeptiven (a 20% concentrate solution for infusion containing N(2)-L-alanyl-L-glutamine). It is an intravenous supplement utilized in clinical nutrition for hypercatabolic states.

Product Overview:

• Active Ingredient: N(2)-L-alanyl-L-glutamine (20 g per 100 ml; 50 ml contains roughly 6.7 g of L-glutamine and 4.1 g of L-alanine).
• Packaging: 50 ml glass bottles/vials, typically supplied in boxes of 10 units.
• Primary Use: Intravenous nutritional supplementation for patients in hypercatabolic or hypermetabolic states (such as severe burns, major surgery, trauma, or critical illness) when oral or enteral feeding is insufficient or impossible.

Kabi Glutamine is recommended for patients with increased glutamine needs, including:

• mucositis caused by chemotherapy or radiotherapy
• chronic inflammatory bowel disease
• short bowel syndrome
• postoperative recovery
• conditions associated with oxidative stress

Administration and Dosage Guidelines:

• Not for Direct Injection: Dipeptiven is a concentrated solution and must never be administered undiluted. It must be mixed with a compatible amino acid carrier solution before infusion.
• Standard Dosage: Usually ranges from 1.5 ml to 2.5 ml of Dipeptiven per kg of body weight daily (equivalent to 0.3g to 0.5g of the dipeptide per kg).
• Infusion Limits: The maximum daily dosage should not exceed 30% of the total amino acid/protein supply.
• Duration: Treatment duration should not exceed 3 weeks.

Safety and Contraindications:

• Contraindications: Do not use in patients with severe renal impairment (creatinine clearance < 25 ml/min), severe hepatic failure, severe metabolic acidosis, or circulatory shock.
• Medical Supervision: Must only be prescribed and managed by qualified healthcare professionals in a clinical or hospital setting

Storage:

• Store in a dry place at room temperature
• Protect from light
• Keep out of reach of children