HANHEAL HAIR FILLER 10amp Sterile

Hanheal Hair Filler is a restorative mesopreparation that helps patients with partial alopecia.

Hanheal Exosome (dry ampoule)

Indications for use

• Hair loss
• Hair depigmentation
• Hair fragility
• Lack of volume
• Dryness, flaking of the scalp, dandruff
• Increased grease, oily hair

Application result

• Ensuring adequate delivery of nutrients necessary for the formation of the hair shaft
• Revival of the structural state of the skin, scalp and the hair follicle itself
• Peptide regulation of receptors responsible for the hair growth phase
• Helps with all types of alopecia, including androgenic
• Improvement of microcirculation and  nutrition of the hair follicle
• Stimulation, microcirculation in the area of the hair follicle
• Anti-inflammatory and immunomodulatory action
• Elimination of microinflammation and local damaging immunological disorders
• Activation of the growth of new hair in the areas of thinning and shedding

Mode of application

• Needle size: 30Gx4, 32Gx4, 0.3×13
  Injection technique: Nappage, Micropapular (Dermapen,  Mesoscoter)
• Volume per injection: 0.1ml
• Total volume: 5.0ml
• Depth of injection: 0.25-2ml

Precautions

• Adults course from 1 to 2 monts
• Teenagers – 1 month

Precautions

Composition & Basic concept

Hanheal Hair Filler:

Water, Sodium Chloride, Glycerin, Butylene Glycol, 1,2-Hexanediol, Ethylhexylglycerin, Copper Tripeptide-1, sh-Decapeptide-9, Biotinoyl Tripeptide-1,
Nicotinoyl Tripeptide-1, sh-Oligopeptide-1,
sh-Oligopeptide-2, sh-Polypeptide-8, sh-Polypeptide-62, sh-Polypeptide-59, sh-Polypeptide-3, sh-Polypeptide-1, sh-Polypeptide-9, sh-Polypeptide-22.

COPPER-1 TRIPEPTIDE (0.5 h/mln)
– During the hair growth phase, collagen and various glycoproteins increase in the cells of the dermal papillae. The ECM components in the hair follicles decrease as the hair enters the telogen phase. Substances that appear during the growth and rest of hair follicles are growth factors directly involved in hair growth.
– Ion Cu promotes the synthesis of these ECM components by interacting with cell fiber bundles and increases the fiber bundle density (number of fibers) of the dermal papilla, helping to regulate the hair growth cycle.
– There is a lot of copper in healthy hair, but it decreases with age. Copper Tripeptide-1 regulates the hair growth cycle, promoting hair growth and reducing hair loss.

• BIOTINOYLTRIPEPTIDE-1 (5 ppb)
Tripeptide, consisting of biotin and three amino acid residues, which is a protein derivative. It reduces the production of DHT (dihydrotestosterone), the main cause of male pattern baldness, increases hair growth, stimulates hair-strengthening genes, and increases the number of hair follicles in the anagen phase, the stage of active hair follicle growth.

• PEPTIDE COMPLEX
(sh-polypeptide-1, sh-polypeptide-3, sh-polypeptide-9, sh-polypeptide-22, sh-oligopeptide-2)

– sh polypeptide-1
This is a basic fibroblast growth factor (bFGF) known as human oligopeptide-3. bFGF is widely distributed in the pituitary gland, brain, kidneys, adrenal glands, follicles, bone matrix, cartilage, endothelial cells, and fibroblasts. RH Polypeptide-1 promotes collagen synthesis in the skin to prevent skin aging and helps in the rapid renewal of keratinocytes in the skin to maintain skin health.
– sh-polypeptide-3
Produces keratin, a major protein for hair, nails and skin. It helps the growth and differentiation of keratinocytes, promotes the separation of skin tissue and epidermis, and also affects skin regeneration. It interacts with EGF, IGF and a / bFGF to prevent skin aging.
– sh-polypeptide-9
It is formed from platelets and participates in the creation of new blood vessels, promoting the division of vascular endothelial cells. It is used as an important factor against aging, damaged skin regeneration, and hair regeneration and growth.
– sh polypeptide-22
It is a growth factor that regulates cell division, differentiation and physiological activity. It plays an important role in the regeneration and healing of wounds on the skin and tissues of the scalp.
– sh-oligopeptide-2
It is the most effective and powerful antioxidant in all cells. It is effective for cell regeneration, antiaging, hair growth and is an antioxidant.

Hanheal Exosome Dry Ampoule

Sodium Hyaluronate, Human dermal fibroblasts induced by multipotent cellular exosomes

SODIUM HYALURONATE (99.99723%)

– It is a biosynthetic natural material that is abundant in the skin and has many hydroxyl groups, so it is a hydrophilic material and plays a role in skin hydration. It can absorb and store moisture up to about 1000 times its own weight, which is why it is a key component of the skin, also called a natural moisturizer.
– Hyaluronic acid has two characteristics at the same time: fast delivery of moisture and strong moisture retention, and therefore is the most optimized ingredient for skin hydration. It is involved in the storage of cell growth factors and nutrients, the maintenance of intercellular space and diffusion, and also plays a role in the elasticity and volume of the skin.
– For sensitive skin, it prevents moisture from evaporating from the skin and at the same time absorbs moisture so that the skin retains proper moisture.

• EXOSOMES of multipotent cells induced by human dermal fibroblasts (27.7 ppm)

– Exosomes are vesicles secreted by cells, derived from certain intracellular organelles called
polycystic bodies, and released from cells. It is secreted by various cells such as lymphocytes, cancer cells, platelets, macrophages, nerve cells, and epithelial cells, and is present in body fluids such as blood, breast milk, cerebrospinal fluid, urine, and ascites. It regulates cell proliferation and differentiation, apoptosis and angiogenesis, and induces intercellular communication.
– In the field of dermatological research, it has been reported that exosomes derived from human umbilical cord mesenchymal stem cells induce regeneration of burnt skin and exhibit wound healing activity.
– It is effective for skin elasticity and regeneration by increasing the collagen precursor procollagen and elastin. When used on the scalp, the number and area of hair follicles in the healthy growth stage with deep and clean roots when treated with hair follicles caused by hair loss, since all the key cells (bulge, hair gem, dermal papilla) that affect hair growth strongly reproduce. They all increase significantly.